General Information
Age Group
AdultsStatus
ActiveProtocol Number
Background Information
The purpose of this research study is to compare the effectiveness of oral sulopenem etzadroxil/probenecid tablets versus oral amoxicillin/clavulanate capsules in adult women with uncomplicated urinary tract infection (UTI). If you are diagnosed with unclomplicated UTI, you will be randomized to one of the two following study treatment groups:
A placebo is an inactive substance that looks like the actual medication but contains no active ingredients. This study is double-blind, which means neither you nor the study doctor evaluating your infection will know if you are assigned to take study drug or comparator study drug. In the event of an emergency, the study doctor can find out which study drug the you are receiving.
- Sulopenem etzadroxil/probenecid 500 mg/500 mg tablet along with a placebo capsule, twice daily for 5 days
- Oral amoxicillin/clavulanate 875 mg/125 mg capsule, along with a placebo tablet, twice daily for 5 days
Offered At
Inova OB-GYN Falls Church
500 N. Washington St. #300
Falls Church, VA 22046
Inova Fairfax Medical Campus
3300 Gallows Rd.
Falls Church, VA 22042
Seyed Shobeiri, MD
Eligibility Information
- 18 years of age or older
- Presenting signs and symptoms of uncomplicated UTI
Ineligibility Information
- Receipt of antibacterial drug therapy potentially effective as treatment of uUTI within the prior 7 days
- You are pregnant, or are currently breastfeeding
- Current resident of a long-term care facility
- Any history of trauma to the pelvis or urinary tract
- Females of child-bearing potential who are unable to take adequate contraceptive precautions
- Poorly controlled diabetes, history of uric acid kidney stones