General Information
Age Group
AdultsStatus
RecruitingProtocol Number
NCT02598349
Background Information
The purpose of this research is to find out what effects, good and/or bad, proton radiation combined with chemotherapy and surgery (if performed) has on you and your pancreatic cancer. The goal is improved disease-free survival. This study will look at the side effects from the treatment and how the tumor responds to the combination of treatment with proton radiation.
Offered At
Inova Schar Cancer Institute
8081 Innovation Park Drive
Fairfax, VA 22031
A Department of Inova Fairfax Hospital
Eligibility Information
- Adults over 18 years of age
- Biopsy proven adenocarcinoma of the pancreas that is unresectable, borderline resectable, medically inoperable, or patient refusing surgery
- ECOG Performance Status 0-2 within 8 weeks prior to study registration
- No evidence of metastatic disease, including ascites and/or peritoneal seeding
- No previous irradiation to the abdomen
- No prior surgical resection of pancreatic cancer
- Additional eligibility in protocol
Ineligibility Information
- Evidence of distant metastasis; metastatic disease in the major viscera (organs); peritoneal seeding
- Previous irradiation to the abdomen
- Prior surgical resection of pancreatic cancer
- Previous history of invasive malignancy (except non-melanoma skin cancer and low to intermediate risk prostate cancer) unless the subject has been disease free for 5 years prior to registration
- Active, untreated infection
- Pregnant and/or breast-feeding women, or patients of child-producing potential not willing to use medically acceptable contraception while on treatment and for at least 12 months thereafter
- Additional ineligibility in protocol
Inclusion of International Subjects
- Patients from outside of the United States may participate in the study. Enrollment and treatment must be completed at an approved PCG member institution
Additional information can be found at: https://clinicaltrials.gov/ct2/show/ NCT02598349