Examining the Microbiome Changes with Fecal Microbiota Transplantation (FMT) for Children with Recurrent Clostridium Difficile Infection
Clostridium difficile infection is an intestinal infection that can be life threatening. The incidence is increasing in children, and there is resistance to standard treatment with rising rates of recurrence. In resistant and recurrent cases, manipulation of the microbiome by FMT is an effective treatment. We are examining the intestinal microbiome in children before and after FMT to gain and better understanding of why this treatment is effective and also to improve FMT treatment in the future.